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A role for a single-stranded junction in RNA binding and specificity by the Tetrahymena group I ribozyme
We have investigated the role of a single-stranded RNA junction, J1/2, that connects the substrate-containing P1 duplex to the remainder of the Tetrahymena group I ribozyme. Single turnover kinetics, fluorescence anisotropy, and single molecule FRET for a series of J1/2 mutants were used to probe th...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3277301/ https://ncbi.nlm.nih.gov/pubmed/22220837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2083575 |
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