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β-Bulge triggers route-switching on the functional landscape of interleukin-1β

Proteins fold into three-dimensional structures in a funneled energy landscape. This landscape is also used for functional activity. Frustration in this landscape can arise from the competing evolutionary pressures of biological function and reliable folding. Thus, the ensemble of partially folded s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Capraro, Dominique T., Roy, Melinda, Onuchic, José N., Gosavi, Shachi, Jennings, Patricia A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277114/
https://ncbi.nlm.nih.gov/pubmed/22307602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114430109
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