β-Bulge triggers route-switching on the functional landscape of interleukin-1β

Proteins fold into three-dimensional structures in a funneled energy landscape. This landscape is also used for functional activity. Frustration in this landscape can arise from the competing evolutionary pressures of biological function and reliable folding. Thus, the ensemble of partially folded s...

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Detaylı Bibliyografya
Asıl Yazarlar: Capraro, Dominique T., Roy, Melinda, Onuchic, José N., Gosavi, Shachi, Jennings, Patricia A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2012
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277114/
https://ncbi.nlm.nih.gov/pubmed/22307602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114430109
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