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Multiple routes lead to the native state in the energy landscape of the β-trefoil family

In general, the energy landscapes of real proteins are sufficiently well designed that the depths of local energetic minima are small compared with the global bias of the native state. Because of the funneled nature of energy landscapes, models that lack energetic frustration have been able to captu...

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Detalhes bibliográficos
Main Authors: Chavez, Leslie L., Gosavi, Shachi, Jennings, Patricia A., Onuchic, José N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502444/
https://ncbi.nlm.nih.gov/pubmed/16801558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510110103
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