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APOE genotype alters glial activation and loss of synaptic markers in mice

The E4 allele of the Apolipoprotein E (APOE) gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD), and affects clinical outcomes of chronic and acute brain damages. The mechanisms by which apoE affect diverse diseases and disorders may involve modulation of the glia...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhu, Yuangui, Nwabuisi-Heath, Evelyn, Dumanis, Sonya B., Tai, Leon, Yu, Chunjiang, Rebeck, G. William, Jo LaDu, Mary
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276698/
https://ncbi.nlm.nih.gov/pubmed/22228589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22289
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