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An erythromycin process improvement using the diethyl methylmalonate responsive (Dmr) phenotype of the Saccharopolyspora erythraea mutB strain
The Saccharopolyspora erythraea mutB knockout strain, FL2281, having a block in the methylmalonyl-CoA mutase reaction, was found to carry a diethyl methylmalonate-responsive (Dmr) phenotype in an oil-based fermentation medium. The Dmr phenotype confers the ability to increase erythromycin A (erythro...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3276693/ https://ncbi.nlm.nih.gov/pubmed/22048617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-011-3650-3 |
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