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Organization of a cluster of erythromycin genes in Saccharopolyspora erythraea.

We used a series of gene disruptions and gene replacements to mutagenically characterize 30 kilobases of DNA in the erythromycin resistance gene (ermE) region of the Saccharopolyspora erythraea chromosome. Five previously undiscovered loci involved in the biosynthesis of erythromycin were found, ery...

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Autors principals: Weber, J M, Leung, J O, Maine, G T, Potenz, R H, Paulus, T J, DeWitt, J P
Format: Artigo
Idioma:Inglês
Publicat: 1990
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC208872/
https://ncbi.nlm.nih.gov/pubmed/2185216
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