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Frameshift Mutagenesis: The Roles of Primer–Template Misalignment and the Nonhomologous End-Joining Pathway in Saccharomyces cerevisiae
Small insertions or deletions that alter the reading frame of a gene typically occur in simple repeats such as mononucleotide runs and are thought to reflect spontaneous primer–template misalignment during DNA replication. The resulting extrahelical repeat is efficiently recognized by the mismatch r...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Genetics Society of America
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3276632/ https://ncbi.nlm.nih.gov/pubmed/22095081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.134890 |
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