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The in Vivo Characterization of Translesion Synthesis Across UV-Induced Lesions in Saccharomyces cerevisiae: Insights Into Polζ- and Polη-Dependent Frameshift Mutagenesis
UV irradiation, a known carcinogen, induces the formation of dipyrimidine dimers with the predominant lesions being cyclobutane pyrimidine dimers (CPDs) and pyrimidine (6-4) pyrimidone adducts (6-4PPs). The relative roles of the yeast translesion synthesis DNA polymerases Polζ and Polη in UV surviva...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Copyright © 2006 by the Genetics Society of America
2006
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1456278/ https://ncbi.nlm.nih.gov/pubmed/16387871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.052480 |
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