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The effect of sequence context on spontaneous Polζ-dependent mutagenesis in Saccharomyces cerevisiae
The Polζ translesion synthesis (TLS) DNA polymerase is responsible for over 50% of spontaneous mutagenesis and virtually all damage-induced mutagenesis in yeast. We previously demonstrated that reversion of the lys2ΔA746 −1 frameshift allele detects a novel type of +1 frameshift that is accompanied...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2330250/ https://ncbi.nlm.nih.gov/pubmed/18276637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn054 |
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