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Formaldehyde-induced mutagenesis in Saccharomyces cerevisiae: molecular properties and the roles of repair and bypass systems

Although DNA-protein cross-links (DPCs) pose a significant threat to genome stability, they remain a poorly understood class of DNA lesions. To define genetic impacts of DPCs on eukaryotic cells in molecular terms, we used a sensitive Saccharomyces cerevisiae frameshift-detection assay to analyze mu...

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Bibliografski detalji
Glavni autori: Grogan, Dennis, Jinks-Robertson, Sue
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591480/
https://ncbi.nlm.nih.gov/pubmed/22197481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2011.12.004
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