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ALK-Activating Homologous Mutations in LTK Induce Cellular Transformation
Leukocyte tyrosine kinase (LTK) is a receptor tyrosine kinase reported to be overexpressed in human leukemia. Though much regarding the function of LTK remains unknown, it shares a high degree of similarity with anaplastic lymphoma kinase (ALK), which is found mutated in human cancer. In order to de...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2012
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3276580/ https://ncbi.nlm.nih.gov/pubmed/22347506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031733 |
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