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CRLF2 and JAK2 in B-Progenitor Acute Lymphoblastic Leukemia: A Novel Association in Oncogenesis

Expression of cytokine receptor-like factor 2 (CRLF2) has recently been shown to be upregulated as well as mutated in populations of B-ALL, including Down syndrome (DS-ALL) patients, which lack recurring chromosomal translocations. Increased CRLF2 expression associates with JAK2 mutation, a combinat...

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Autors principals: Roll, J. Devon, Reuther, Gary W.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948596/
https://ncbi.nlm.nih.gov/pubmed/20807819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1528
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