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ALK-Activating Homologous Mutations in LTK Induce Cellular Transformation

Leukocyte tyrosine kinase (LTK) is a receptor tyrosine kinase reported to be overexpressed in human leukemia. Though much regarding the function of LTK remains unknown, it shares a high degree of similarity with anaplastic lymphoma kinase (ALK), which is found mutated in human cancer. In order to de...

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Autors principals: Roll, J. Devon, Reuther, Gary W.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276580/
https://ncbi.nlm.nih.gov/pubmed/22347506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031733
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