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Mutations in the Transmembrane and Juxtamembrane Domains Enhance IL27R Transforming Activity

Cytokines and their receptors regulate hematopoiesis by controlling cellular growth, survival, and differentiation. Thus, it is not surprising that mutations of cytokine receptors contribute to the formation of hematopoietic disorders including cancer. We recently identified transforming properties...

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Autors principals: Lambert, Que T., Pradhan, Anuradha, Roll, J. Devon, Reuther, Gary W.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145822/
https://ncbi.nlm.nih.gov/pubmed/21631431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20110351
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