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Mutations in the Transmembrane and Juxtamembrane Domains Enhance IL27R Transforming Activity
Cytokines and their receptors regulate hematopoiesis by controlling cellular growth, survival, and differentiation. Thus, it is not surprising that mutations of cytokine receptors contribute to the formation of hematopoietic disorders including cancer. We recently identified transforming properties...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3145822/ https://ncbi.nlm.nih.gov/pubmed/21631431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20110351 |
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