Purification of CFTR for mass spectrometry analysis: identification of palmitoylation and other post-translational modifications

Post-translational modifications (PTMs) play a crucial role during biogenesis of many transmembrane proteins. Previously, it had not been possible to evaluate PTMs in cystic fibrosis transmembrane conductance regulator (CFTR), the epithelial ion channel responsible for cystic fibrosis, because of di...

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Hlavní autoři: McClure, Michelle, DeLucas, Lawrence J., Wilson, Landon, Ray, Marjorie, Rowe, Steven M., Wu, Xiaoyun, Dai, Qun, Hong, Jeong S., Sorscher, Eric J., Kappes, John C., Barnes, Stephen
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276306/
https://ncbi.nlm.nih.gov/pubmed/22119790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzr054
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