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Purification of CFTR for mass spectrometry analysis: identification of palmitoylation and other post-translational modifications

Post-translational modifications (PTMs) play a crucial role during biogenesis of many transmembrane proteins. Previously, it had not been possible to evaluate PTMs in cystic fibrosis transmembrane conductance regulator (CFTR), the epithelial ion channel responsible for cystic fibrosis, because of di...

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Detalhes bibliográficos
Main Authors: McClure, Michelle, DeLucas, Lawrence J., Wilson, Landon, Ray, Marjorie, Rowe, Steven M., Wu, Xiaoyun, Dai, Qun, Hong, Jeong S., Sorscher, Eric J., Kappes, John C., Barnes, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276306/
https://ncbi.nlm.nih.gov/pubmed/22119790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzr054
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