Purification of CFTR for mass spectrometry analysis: identification of palmitoylation and other post-translational modifications

Post-translational modifications (PTMs) play a crucial role during biogenesis of many transmembrane proteins. Previously, it had not been possible to evaluate PTMs in cystic fibrosis transmembrane conductance regulator (CFTR), the epithelial ion channel responsible for cystic fibrosis, because of di...

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Autors principals: McClure, Michelle, DeLucas, Lawrence J., Wilson, Landon, Ray, Marjorie, Rowe, Steven M., Wu, Xiaoyun, Dai, Qun, Hong, Jeong S., Sorscher, Eric J., Kappes, John C., Barnes, Stephen
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276306/
https://ncbi.nlm.nih.gov/pubmed/22119790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzr054
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