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Plant-based Expression of a Partially Humanized Neutralizing Monoclonal IgG Directed against an Immunodominant Epitope on the Ricin Toxin A Subunit
GD12 is a murine monoclonal IgG(1) (mAb) that recognizes an immunodominant linear neutralizing epitope (163-TLARSFIICIQM-174) on the A subunit (RTA) of ricin toxin. With the long-term goal of using GD12 as a potential countermeasure against ricin intoxication, we have produced a chimeric derivative...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3274600/ https://ncbi.nlm.nih.gov/pubmed/22197964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.12.058 |
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