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A Monoclonal Immunoglobulin G Antibody Directed against an Immunodominant Linear Epitope on the Ricin A Chain Confers Systemic and Mucosal Immunity to Ricin

Due to the potential use of ricin and other fast-acting toxins as agents of bioterrorism, there is an urgent need for the development of safe and effective antitoxin vaccines. A candidate ricin subunit vaccine (RiVax) consisting of a recombinant attenuated enzymatic A chain (RTA) has been shown to e...

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Main Authors: Neal, Lori M., O'Hara, Joanne, Brey, Robert N., Mantis, Nicholas J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798177/
https://ncbi.nlm.nih.gov/pubmed/19858297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00796-09
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