SMARCAL1 catalyzes fork regression and Holliday junction migration to maintain genome stability during DNA replication

SMARCAL1 (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily A-like1) maintains genome integrity during DNA replication. Here we investigated its mechanism of action. We found that SMARCAL1 travels with elongating replication forks, and its absence leads to MUS81-d...

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Hlavní autoři: Bétous, Rémy, Mason, Aaron C., Rambo, Robert P., Bansbach, Carol E., Badu-Nkansah, Akosua, Sirbu, Bianca M., Eichman, Brandt F., Cortez, David
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2012
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273839/
https://ncbi.nlm.nih.gov/pubmed/22279047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.178459.111
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