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Topological constraints impair RNA polymerase II transcription and causes instability of plasmid-borne convergent genes

Despite the theoretical bases for the association of topoisomerases and supercoiling changes with transcription and replication, our knowledge of the impact of topological constraints on transcription and replication is incomplete. Although mutation of topoisomerases affects expression and stability...

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Detalhes bibliográficos
Main Authors: García-Rubio, María L., Aguilera, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273821/
https://ncbi.nlm.nih.gov/pubmed/21998294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr840
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