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Matrix metalloproteinase (MMP)-dependent microsomal prostaglandin E synthase (mPGES)-1 expression in macrophages: Role of TNF-α and the EP4 prostanoid receptor(1)

MMP-9 contributes to the pathogenesis of chronic inflammatory diseases and cancer. Thus, identifying targetable components of signaling pathways that regulate MMP-9 expression may have broad therapeutic implications. Our previous studies revealed a nexus between metalloproteinases and prostanoids wh...

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Autors principals: Khan, K.M. Faisal, Kothari, Poonam, Du, Baoheng, Dannenberg, Andrew J., Falcone, Domenick J.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273587/
https://ncbi.nlm.nih.gov/pubmed/22227567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102383
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