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Matrix metalloproteinase (MMP)-1 and MMP-3 induce macrophage MMP-9: Evidence for the role of TNF-α and cyclooxygenase-2

MMP-9 (gelatinase B) participates in a variety of diverse physiologic and pathologic processes. We recently characterized a cyclooxygenase-2 (Cox-2)→PGE(2)→EP4 receptor axis that regulates macrophage MMP-9 expression. In the current studies, we determined whether MMPs, commonly found in inflamed and...

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Bibliografiset tiedot
Päätekijät: Steenport, Michel, Faisal Khan, K.M., Du, Baoheng, Barnhard, Sarah E., Dannenberg, Andrew J., Falcone, Domenick J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621723/
https://ncbi.nlm.nih.gov/pubmed/19923455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901925
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