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Matrix metalloproteinase (MMP)-1 and MMP-3 induce macrophage MMP-9: Evidence for the role of TNF-α and cyclooxygenase-2
MMP-9 (gelatinase B) participates in a variety of diverse physiologic and pathologic processes. We recently characterized a cyclooxygenase-2 (Cox-2)→PGE(2)→EP4 receptor axis that regulates macrophage MMP-9 expression. In the current studies, we determined whether MMPs, commonly found in inflamed and...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3621723/ https://ncbi.nlm.nih.gov/pubmed/19923455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901925 |
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