Fatty acid–binding protein 5 controls microsomal prostaglandin E synthase 1 (mPGES-1) induction during inflammation

Fatty acid–binding proteins (FABPs) are intracellular lipid carriers that regulate inflammation, and pharmacological inhibition of FABP5 reduces inflammation and pain. The mechanism(s) underlying the anti-inflammatory effects associated with FABP5 inhibition is poorly understood. Herein, we identify...

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Vydáno v:J Biol Chem
Hlavní autoři: Bogdan, Diane, Falcone, Jerome, Kanjiya, Martha P., Park, Sang Hoon, Carbonetti, Gregory, Studholme, Keith, Gomez, Maria, Lu, Yong, Elmes, Matthew W., Smietalo, Norbert, Yan, Su, Ojima, Iwao, Puopolo, Michelino, Kaczocha, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892576/
https://ncbi.nlm.nih.gov/pubmed/29440395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001593
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