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tRNAs marked with CCACCA are targeted for degradation
The CCA-adding enzyme [ATP(CTP):tRNA nucleotidyltransferase] adds CCA to the 3′ ends of transfer RNAs (tRNAs), a critical step in tRNA biogenesis that generates the amino acid attachment site. Here, we show that the CCA-adding enzyme plays a key role in tRNA quality control as it selectively marks s...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3273417/ https://ncbi.nlm.nih.gov/pubmed/22076379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1213671 |
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