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Identification and analysis of tRNAs that are degraded in Saccharomyces cerevisiae due to lack of modifications

There is mounting evidence that tRNA modifications play crucial roles in the maintenance of wild type levels of several tRNA species. Here we describe a generalized framework in which to study tRNA turnover in the yeast Saccharomyces cerevisiae as a consequence of a defect in tRNA modification statu...

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Détails bibliographiques
Auteurs principaux: Chernyakov, Irina, Baker, Melanie A., Grayhack, Elizabeth J., Phizicky, Eric M.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788775/
https://ncbi.nlm.nih.gov/pubmed/19215761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0076-6879(08)02411-7
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