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The yeast rapid tRNA decay pathway competes with elongation factor 1A for substrate tRNAs and acts on tRNAs lacking one or more of several modifications
The structural and functional integrity of tRNA is crucial for translation. In the yeast Saccharomyces cerevisiae, certain aberrant pre-tRNA species are subject to nuclear surveillance, leading to 3′ exonucleolytic degradation, and certain mature tRNA species are subject to rapid tRNA decay (RTD) if...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2012
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3446711/ https://ncbi.nlm.nih.gov/pubmed/22895820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.033654.112 |
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