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The yeast rapid tRNA decay pathway competes with elongation factor 1A for substrate tRNAs and acts on tRNAs lacking one or more of several modifications

The structural and functional integrity of tRNA is crucial for translation. In the yeast Saccharomyces cerevisiae, certain aberrant pre-tRNA species are subject to nuclear surveillance, leading to 3′ exonucleolytic degradation, and certain mature tRNA species are subject to rapid tRNA decay (RTD) if...

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Detalhes bibliográficos
Main Authors: Dewe, Joshua M., Whipple, Joseph M., Chernyakov, Irina, Jaramillo, Laura N., Phizicky, Eric M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446711/
https://ncbi.nlm.nih.gov/pubmed/22895820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.033654.112
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