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Resolving Phenylalanine Metabolism Sheds Light on Natural Synthesis of Penicillin G in Penicillium chrysogenum

The industrial production of penicillin G by Penicillium chrysogenum requires the supplementation of the growth medium with the side chain precursor phenylacetate. The growth of P. chrysogenum with phenylalanine as the sole nitrogen source resulted in the extracellular production of phenylacetate an...

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Main Authors: Veiga, Tânia, Solis-Escalante, Daniel, Romagnoli, Gabriele, ten Pierick, Angela, Hanemaaijer, Mark, Deshmuhk, Amit, Wahl, Aljoscha, Pronk, Jack T., Daran, Jean-Marc
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272894/
https://ncbi.nlm.nih.gov/pubmed/22158714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.05285-11
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