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Resolving Phenylalanine Metabolism Sheds Light on Natural Synthesis of Penicillin G in Penicillium chrysogenum

The industrial production of penicillin G by Penicillium chrysogenum requires the supplementation of the growth medium with the side chain precursor phenylacetate. The growth of P. chrysogenum with phenylalanine as the sole nitrogen source resulted in the extracellular production of phenylacetate an...

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Hlavní autoři: Veiga, Tânia, Solis-Escalante, Daniel, Romagnoli, Gabriele, ten Pierick, Angela, Hanemaaijer, Mark, Deshmuhk, Amit, Wahl, Aljoscha, Pronk, Jack T., Daran, Jean-Marc
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272894/
https://ncbi.nlm.nih.gov/pubmed/22158714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.05285-11
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