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Resolving Phenylalanine Metabolism Sheds Light on Natural Synthesis of Penicillin G in Penicillium chrysogenum

The industrial production of penicillin G by Penicillium chrysogenum requires the supplementation of the growth medium with the side chain precursor phenylacetate. The growth of P. chrysogenum with phenylalanine as the sole nitrogen source resulted in the extracellular production of phenylacetate an...

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Bibliographische Detailangaben
Hauptverfasser: Veiga, Tânia, Solis-Escalante, Daniel, Romagnoli, Gabriele, ten Pierick, Angela, Hanemaaijer, Mark, Deshmuhk, Amit, Wahl, Aljoscha, Pronk, Jack T., Daran, Jean-Marc
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2012
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272894/
https://ncbi.nlm.nih.gov/pubmed/22158714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.05285-11
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