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Substrate cycles in Penicillium chrysogenum quantified by isotopic non-stationary flux analysis

BACKGROUND: Penicillium chrysogenum, the main production strain for penicillin-G, has a high content of intracellular carbohydrates, especially reduced sugars such as mannitol, arabitol, erythritol, as well as trehalose and glycogen. In previous steady state (13)C wash-in experiments a delay of labe...

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Detalhes bibliográficos
Main Authors: Zhao, Zheng, ten Pierick, Angela, de Jonge, Lodewijk, Heijnen, Joseph J, Wahl, S Aljoscha
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538697/
https://ncbi.nlm.nih.gov/pubmed/23098235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-11-140
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