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Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor

Albumin is the most abundant protein in blood where it has a pivotal role as a transporter of fatty acids and drugs. Like IgG, albumin has long serum half-life, protected from degradation by pH-dependent recycling mediated by interaction with the neonatal Fc receptor, FcRn. Although the FcRn interac...

詳細記述

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書誌詳細
主要な著者: Andersen, Jan Terje, Dalhus, Bjørn, Cameron, Jason, Daba, Muluneh Bekele, Plumridge, Andrew, Evans, Leslie, Brennan, Stephan O., Gunnarsen, Kristin Støen, Bjørås, Magnar, Sleep, Darrell, Sandlie, Inger
フォーマット: Artigo
言語:Inglês
出版事項: Nature Pub. Group 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272563/
https://ncbi.nlm.nih.gov/pubmed/22215085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1607
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