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Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor
Albumin is the most abundant protein in blood where it has a pivotal role as a transporter of fatty acids and drugs. Like IgG, albumin has long serum half-life, protected from degradation by pH-dependent recycling mediated by interaction with the neonatal Fc receptor, FcRn. Although the FcRn interac...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Pub. Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3272563/ https://ncbi.nlm.nih.gov/pubmed/22215085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1607 |
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