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Identification of Inhibitors of the Leishmania cdc2-Related Protein Kinase CRK3
New drugs are urgently needed for the treatment of tropical parasitic diseases such as leishmaniasis and human African trypanosomiasis (HAT). This work involved a high-throughput screen of a focussed kinase set of ∼3400 compounds to identify potent and parasite-selective inhibitors of an enzymatic L...
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| Главные авторы: | , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
WILEY-VCH Verlag
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3272345/ https://ncbi.nlm.nih.gov/pubmed/21913331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201100344 |
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