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Protein topology determines binding mechanism
Protein recognition and binding, which result in either transient or long-lived complexes, play a fundamental role in many biological functions, but sometimes also result in pathologic aggregates. We use a simplified simulation model to survey a range of systems where two highly flexible protein cha...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC327178/ https://ncbi.nlm.nih.gov/pubmed/14694192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2534828100 |
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