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Quantitative criteria for native energetic heterogeneity influences in the prediction of protein folding kinetics

Energy landscape theory requires that the protein-folding mechanism is generally globally directed or funneled toward the native state. The collective nature of transition state ensembles further suggests that sufficient averaging of the native interactions can occur so that the knowledge of the nat...

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Detalhes bibliográficos
Main Authors: Cho, Samuel S., Levy, Yaakov, Wolynes, Peter G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626720/
https://ncbi.nlm.nih.gov/pubmed/19075236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810218105
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