Deletion of the SPARC acidic domain or EGF-like module reduces SPARC-induced migration and signaling through p38 MAPK/HSP27 in glioma

We previously demonstrated that secreted protein acidic and rich in cysteine (SPARC) increases heat shock protein 27 (HSP27) expression and phosphorylation and promotes glioma cell migration through the p38 mitogen-activated protein kinase (MAPK)/HSP27 signaling pathway. As different regions of the...

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Detalhes bibliográficos
Main Authors: McClung, Heather M., Golembieski, William A., Schultz, Chad R., Jankowski, Michelle, Schultz, Lonni R., Rempel, Sandra A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Biology, Genetics and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271264/
https://ncbi.nlm.nih.gov/pubmed/22114076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr276
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