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Impaired p38 MAPK/HSP27 signaling underlies aging-related failure in opioid-mediated cardioprotection
Cardioprotection and preconditioning mediated via G-protein-coupled receptors may be lost or impaired with advancing age, limiting ischemic tolerance and the ability to pharmacologically protect older hearts from ischemic injury. Our preliminary findings indicated a loss of δ-opioid receptor-mediate...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2497430/ https://ncbi.nlm.nih.gov/pubmed/17407780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2007.02.011 |
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