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Role of TLR4-p38 MAPK-Hsp27 signal pathway in LPS-induced pulmonary epithelial hyperpermeability

BACKGROUND: The breakdown of alveolar barrier dysfunction contributes to Lipopolysaccharide stimulated pulmonary edema and acute lung injury. Actin cytoskeleton has been implicated to be critical in regulation of epithelial barrier. Here, we performed in vivo and in vitro study to investigate role o...

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Detalles Bibliográficos
Publicado en:BMC Pulm Med
Main Authors: Wang, Weiju, Weng, Jie, Yu, Lei, Huang, Qiaobing, Jiang, Yong, Guo, Xiaohua
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258407/
https://ncbi.nlm.nih.gov/pubmed/30482200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-018-0735-0
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