The evolution of transmembrane helix kinks and the structural diversity of G protein-coupled receptors
One of the hallmarks of membrane protein structure is the high frequency of transmembrane helix kinks, which commonly occur at proline residues. Because the proline side chain usually precludes normal helix geometry, it is reasonable to expect that proline residues generate these kinks. We observe,...
Gardado en:
| Publicado en: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327124/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14732697/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0306077101 |
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