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The tethered configuration of the EGF receptor extracellular domain exerts only a limited control of receptor function

Quantitative epidermal growth factor (EGF)-binding experiments have shown that the EGF-receptor (EGFR) is displayed on the surface of intact cells in two forms, a minority of high-affinity and a majority of low-affinity EGFRs. On the basis of the three-dimensional structure of the extracellular liga...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Mattoon, Dawn, Klein, Peter, Lemmon, Mark A., Lax, Irit, Schlessinger, Joseph
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2004
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC327118/
https://ncbi.nlm.nih.gov/pubmed/14732693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307286101
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