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ONCOGENE MUTATION PROFILING OF PEDIATRIC SOLID TUMORS REVEALS SIGNIFICANT SUBSETS OF EMBRYONAL RHABDOMYOSARCOMA AND NEUROBLASTOMA WITH MUTATED GENES IN GROWTH SIGNALING PATHWAYS

Compared to the numerous broad screens for oncogene mutations in adult cancers, very few have been performed in pediatric solid tumors. To identify novel mutations and potential therapeutic targets in pediatric cancers, we performed a high-throughput Sequenom-based analysis in large sets of several...

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Detalhes bibliográficos
Main Authors: Shukla, Neerav, Ameur, Nabahet, Yilmaz, Ismail, Nafa, Khedoudja, Lau, Chyau-Yueh, Marchetti, Angela, Borsu, Laetitia, Barr, Frederic G., Ladanyi, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271129/
https://ncbi.nlm.nih.gov/pubmed/22142829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-2056
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