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Novel Oncogene and Tumor Suppressor Mutations in KIT and PDGFRA Wild Type Gastrointestinal Stromal Tumors Revealed by Next Generation Sequencing
Among gastrointestinal stromal tumors (GISTs) of 10–15% are negative for KIT and PDGFRA, and most of these cases are SDH deficient. Recent studies have provided data on additional molecular alterations such as KRAS in KIT mutant GISTs. We aimed to assess the frequency and spectrum of somatic mutatio...
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| Publicado no: | Genes Chromosomes Cancer |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6452627/ https://ncbi.nlm.nih.gov/pubmed/25427437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22230 |
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