Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology

The identification of specific genetic alterations as key oncogenic drivers and the development of targeted therapies are together transforming clinical oncology and creating a pressing need for increased breadth and throughput of clinical genotyping. Next-generation sequencing assays allow the effi...

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Publicado no:J Mol Diagn
Main Authors: Cheng, Donavan T., Mitchell, Talia N., Zehir, Ahmet, Shah, Ronak H., Benayed, Ryma, Syed, Aijazuddin, Chandramohan, Raghu, Liu, Zhen Yu, Won, Helen H., Scott, Sasinya N., Brannon, A. Rose, O'Reilly, Catherine, Sadowska, Justyna, Casanova, Jacklyn, Yannes, Angela, Hechtman, Jaclyn F., Yao, Jinjuan, Song, Wei, Ross, Dara S., Oultache, Alifya, Dogan, Snjezana, Borsu, Laetitia, Hameed, Meera, Nafa, Khedoudja, Arcila, Maria E., Ladanyi, Marc, Berger, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808190/
https://ncbi.nlm.nih.gov/pubmed/25801821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2014.12.006
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