Comprehensive detection of germline variants by MSK-IMPACT, a clinical diagnostic platform for solid tumor molecular oncology and concurrent cancer predisposition testing

BACKGROUND: The growing number of Next Generation Sequencing (NGS) tests is transforming the routine clinical diagnosis of hereditary cancers. Identifying whether a cancer is the result of an underlying disease-causing mutation in a cancer predisposition gene is not only diagnostic for a cancer pred...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:BMC Med Genomics
Autori principali: Cheng, Donavan T., Prasad, Meera, Chekaluk, Yvonne, Benayed, Ryma, Sadowska, Justyna, Zehir, Ahmet, Syed, Aijazuddin, Wang, Yan Elsa, Somar, Joshua, Li, Yirong, Yelskaya, Zarina, Wong, Donna, Robson, Mark E., Offit, Kenneth, Berger, Michael F., Nafa, Khedoudja, Ladanyi, Marc, Zhang, Liying
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Technical Advance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437632/
https://ncbi.nlm.nih.gov/pubmed/28526081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-017-0271-4
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi