Intratumoral KIT mutational heterogeneity and recurrent KIT/ PDGFRA mutations in KIT/PDGFRA wild-type gastrointestinal stromal tumors

OBJECTIVE: Gastrointestinal stromal tumors (GISTs) with no mutations in exons 9, 11, 13, and 17 of the KIT gene and exons 12, and 18 of the PDGFRA gene were defined as KIT/PDGFRA wild-type and they accounted for ~15–20% of GISTs. However, some KIT/PDGFRA wild-type GISTs with KIT mutations in other e...

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Published in:Oncotarget
Main Authors: Gao, Jing, Li, Jian, Li, Yanyan, Li, Zhongwu, Gong, Jifang, Wu, Jian, Liu, Na, Dong, Bin, Qi, Changsong, Li, Jie, Shen, Lin
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058677/
https://ncbi.nlm.nih.gov/pubmed/26848617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7148
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