Intratumoral KIT mutational heterogeneity and recurrent KIT/ PDGFRA mutations in KIT/PDGFRA wild-type gastrointestinal stromal tumors

OBJECTIVE: Gastrointestinal stromal tumors (GISTs) with no mutations in exons 9, 11, 13, and 17 of the KIT gene and exons 12, and 18 of the PDGFRA gene were defined as KIT/PDGFRA wild-type and they accounted for ~15–20% of GISTs. However, some KIT/PDGFRA wild-type GISTs with KIT mutations in other e...

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Foilsithe in:Oncotarget
Main Authors: Gao, Jing, Li, Jian, Li, Yanyan, Li, Zhongwu, Gong, Jifang, Wu, Jian, Liu, Na, Dong, Bin, Qi, Changsong, Li, Jie, Shen, Lin
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2016
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058677/
https://ncbi.nlm.nih.gov/pubmed/26848617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7148
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