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The genetic landscape of gastrointestinal stromal tumor lacking KIT and PDGFRA mutations

About 10–15 % of adult gastrointestinal stromal tumors (GISTs) and 85 % of pediatric GISTs do not have mutations in the KIT or PDGFRA genes and are generally classified as KIT/PDGFRA wild type (WT). Recent studies have shown that this group of KIT/PDGFRA WT GISTs is quite heterogeneous in terms of c...

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Detalles Bibliográficos
Publicado en:Endocrine
Main Authors: Boikos, Sosipatros A., Stratakis, Constantine A.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729312/
https://ncbi.nlm.nih.gov/pubmed/25027296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12020-014-0346-3
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