Molecular Subtypes of KIT/PDGFRA Wild-Type Gastrointestinal Stromal Tumors: A Report From the National Institutes of Health Gastrointestinal Stromal Tumor Clinic

IMPORTANCE: Wild-type (WT) gastrointestinal stromal tumors (GISTs), which lack KIT and PDGFRA gene mutations, are the primary form of GIST in children and occasionally occur in adults. They respond poorly to standard targeted therapy. Better molecular and clinical characterization could improve mana...

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Detaylı Bibliyografya
Yayımlandı:JAMA Oncol
Asıl Yazarlar: Boikos, Sosipatros A., Pappo, Alberto S., Killian, J. Keith, LaQuaglia, Michael P., Weldon, Chris B., George, Suzanne, Trent, Jonathan C., von Mehren, Margaret, Wright, Jennifer A., Schiffman, Josh D., Raygada, Margarita, Pacak, Karel, Meltzer, Paul S., Miettinen, Markku M., Stratakis, Constantine, Janeway, Katherine A., Helman, Lee J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472100/
https://ncbi.nlm.nih.gov/pubmed/27011036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2016.0256
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