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Accumulation of CCR4(+) CTLA-4(hi) FOXP3(+)CD25(hi) Regulatory T Cells in Colon Adenocarcinomas Correlate to Reduced Activation of Conventional T Cells
BACKGROUND: Colorectal cancer usually gives rise to a specific anti-tumor immune response, but for unknown reasons the resulting immunity is not able to clear the tumor. Recruitment of activated effector lymphocytes to the tumor is important for efficient anti-tumor responses, while the presence of...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3271060/ https://ncbi.nlm.nih.gov/pubmed/22319577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030695 |
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