Regulatory T cells control endothelial chemokine production and migration of T cells into intestinal tumors of APC(min/+) mice

Tumor-infiltrating lymphocytes are crucial for anti-tumor immunity. We have previously shown that regulatory T cells (Treg) are able to reduce T-cell transendothelial migration in vitro and accumulation of effector T cells in intestinal tumors in vivo. Treg depletion also resulted in increased level...

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Udgivet i:Cancer Immunol Immunother
Main Authors: Akeus, Paulina, Szeponik, Louis, Ahlmanner, Filip, Sundström, Patrik, Alsén, Samuel, Gustavsson, Bengt, Sparwasser, Tim, Raghavan, Sukanya, Quiding-Järbrink, Marianne
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2018
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006230/
https://ncbi.nlm.nih.gov/pubmed/29671006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-018-2161-9
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