Tumor-infiltrating mucosal-associated invariant T (MAIT) cells retain expression of cytotoxic effector molecules

Mucosal-associated invariant T (MAIT) cells all express a semi-invariable T cell receptor recognizing microbial metabolites presented on the MHC class I-like molecule MR1. Upon activation, they rapidly secrete cytokines and increase their cytotoxic potential. We showed recently that MAIT cells with...

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Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Sundström, Patrik, Szeponik, Louis, Ahlmanner, Filip, Sundquist, Malin, Wong, Justin S.B., Lindskog, Elinor Bexe, Gustafsson, Bengt, Quiding-Järbrink, Marianne
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2019
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497460/
https://ncbi.nlm.nih.gov/pubmed/31073372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26866
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